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Focal Necrotising Herpes Simplex Encephalitis:Two Cases with Good Clinical & Neuropsychological Outcomes
JNNP 57:1115-1117, Counsell,C.E.,et al, 1994
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Article Abstract
Two patients with atypical focal necrotising herpes simplex encephalitis are described.They presented with relatively mild clinical disease but despite treatment with acyclovir(10 mg/kg/day for three days in case 1 and 10 days in case 2)they developed dramatic,progressive changes(shown on brain CT)that mimicked space occupying lesions of the temporal lobes.Both patients therefore had a diagnostic and therapeutic temporal lesionectomy followed by further 10 day courses of acyclovir.They subsequently went on to make good clinical and neuropsychological recoveries.
 
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brain biopsy
CAT scan
CAT scan,abnormal
CAT scan,ring sign
encephalitis,focal
herpes simplex encephalitis
herpes simplex encephalitis,differential diagnosis of
temporal lobectomy

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